Ptf1a Antibody - N-terminal region : HRP (ARP37243_P050-HRP)
Selected Variant
ARP37243_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Pancreas specific transcription factor, 1a
Gene Aliases
BHLHa, PTF1-p, PTF1p48, bHLHa29, PTF1-p48
Gene ID
19213
Swiss Prot
Q9QX98
Accession Number
NP_061279
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Ptf1a
Target
Ptf1a is a transcriptional activator. It binds to the E-box consensus sequence 5'-CANNTG-3' and may play a role in early and late pancreas development and differentiation. Ptf1a plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates and may be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. It is required for the formation of pancreatic acinar and ductal cells. and plays an important role in cerebellar development.
Partner Proteins
Rbpj
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 86%; Horse: 92%; Human: 93%; Mouse: 100%; Pig: 93%; Rat: 93%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
35kDa
Shipping Conditions
Wet Ice
Protein Length
324
NCBI Gene Symbol
PTF1A
NCBI GB Accession Number
Ptf1a
Host or Source
Rabbit
Protein Name
Pancreas transcription factor 1 subunit alpha
Nucleotide Accession Number
NM_018809
Peptide Sequence
FPSPYFDEEDFFTDQSSRDPLEDSDELLGDEQAEVEFLSHQLHEYCYRDG
Subunit
Alpha
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