IRF5 Antibody - N-terminal region : HRP (ARP37180_P050-HRP)
Selected Variant
ARP37180_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Interferon regulatory factor 5
Gene Aliases
Mir, mirf5, AW491843
Gene ID
27056
Swiss Prot
P56477
Accession Number
NP_036187
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF5
Target
The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
Partner Proteins
Ubc; Traf6; Irak1; Zfp764; Myd88; Il12b
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Mouse: 100%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
55kDa
References & Citations
Takaoka, A., et al., (2005) Nature 434 (7030), 243-249
Shipping Conditions
Wet Ice
Protein Length
497
NCBI Gene Symbol
IRF5
NCBI GB Accession Number
IRF5
Host or Source
Rabbit
Protein Name
Interferon regulatory factor 5
Nucleotide Accession Number
NM_012057
Peptide Sequence
CSNGPAPTESQPTDDYVLGEEEEEEEEELQRMLPGLSITEPALPGPPNAP
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