SREBF1 Antibody - N-terminal region : Biotin (ARP37145_P050-Biotin)
Product Specifications
Gene Name
Sterol regulatory element binding transcription factor 1
Gene Aliases
SRE, ADD-, ADD1, SREB, SREBP, bHLHd, SREBP1, bHLHd1
Gene ID
20787
Swiss Prot
Q9WTN3
Accession Number
NP_035610
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of mouse SREBF1
Target
Srebf1 is transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') . Srebf1 also binds to an E-box motif (5'-ATCACGTGA-3') . Srebf1 regulates the transcription of genes for sterol biosynthesis and the LDL receptor gene.
Partner Proteins
Rnf20; Zbtb7c; Ppargc1b; Rela; Ewsr1; Pcbd1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Mouse: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
125kDa
References & Citations
Briancon, N. (2006) EMBO J. 25 (6), 1253-1262
Shipping Conditions
Wet Ice
Protein Length
1134
NCBI Gene Symbol
SREBF1
NCBI GB Accession Number
SREBF1
Host or Source
Rabbit
Protein Name
Sterol regulatory element-binding protein 1
Nucleotide Accession Number
NM_011480
Peptide Sequence
DIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPSSPGANSPESFSSASL
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