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SREBF1 Antibody - N-terminal region : FITC (ARP37145_P050-FITC)

Selected Variant

ARP37145_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Sterol regulatory element binding transcription factor 1

Gene Aliases

SRE, ADD-, ADD1, SREB, SREBP, bHLHd, SREBP1, bHLHd1

Gene ID

20787

Swiss Prot

Q9WTN3

Accession Number

NP_035610

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of mouse SREBF1

Target

Srebf1 is transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') . Srebf1 also binds to an E-box motif (5'-ATCACGTGA-3') . Srebf1 regulates the transcription of genes for sterol biosynthesis and the LDL receptor gene.

Partner Proteins

Rnf20; Zbtb7c; Ppargc1b; Rela; Ewsr1; Pcbd1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Mouse: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

125kDa

References & Citations

Briancon, N. (2006) EMBO J. 25 (6), 1253-1262

Shipping Conditions

Wet Ice

Protein Length

1134

NCBI Gene Symbol

SREBF1

NCBI GB Accession Number

SREBF1

Host or Source

Rabbit

Protein Name

Sterol regulatory element-binding protein 1

Nucleotide Accession Number

NM_011480

Peptide Sequence

DIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPSSPGANSPESFSSASL

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