NR1I3 Antibody - C-terminal region : Biotin (ARP37028_T100-Biotin)
Selected Variant
ARP37028_T100-Biotin
Size: 100 µL
Product Specifications
Gene Name
Nuclear receptor subfamily 1, group I, member 3
Gene Aliases
C, CA, mC, CAR, MB67, Care2, ESTM3, ESTM32, AA209988, AI551208, CAR-beta
Gene ID
12355
Swiss Prot
O35627
Accession Number
NP_033933
Host
Rabbit
Reactivity
Mouse
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of mouse NR1I3
Target
NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
Partner Proteins
NCOR2; Ppp2r1a; Ppp2ca; Hsp90ab1; Psmc4; NR0B2; Ncoa1; Ncor1; Rxrg; NCOA6
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Mouse: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
39kDa
References & Citations
Briancon, N. (2006) EMBO J. 25 (6), 1253-1262
Shipping Conditions
Wet Ice
Protein Length
358
NCBI Gene Symbol
NR1I3
NCBI GB Accession Number
NR1I3
Host or Source
Rabbit
Protein Name
Nuclear receptor subfamily 1 group I member 3
Nucleotide Accession Number
NM_009803
Peptide Sequence
QQSRLQSRFLYAKLMGLLADLRSINNAYSYELQRLEELSAMTPLLGEICS
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