Tfam Antibody - C-terminal region : HRP (ARP36993_P050-HRP)
Selected Variant
ARP36993_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Transcription factor A, mitochondrial
Gene Aliases
Hmgt, mtTF, tsHM, Hmgts, mtTFA, tsHMG, AI661103
Gene ID
21780
Swiss Prot
P40630
Accession Number
NP_033386
Host
Rabbit
Reactivity
Mouse, Rat, Cow, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of mouse Tfam
Target
TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Partner Proteins
C1QBP; SNCA
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Mouse: 100%; Rabbit: 79%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
References & Citations
Noack, H., (2006) Biochim. Biophys. Acta 1760 (2), 141-150
Shipping Conditions
Wet Ice
Protein Length
243
NCBI Gene Symbol
TFAM
NCBI GB Accession Number
Tfam
Host or Source
Rabbit
Protein Name
Transcription factor A, mitochondrial
Nucleotide Accession Number
NM_009360
Peptide Sequence
FQEAKDDSAQGKLKLVNEAWKNLSPEEKQAYIQLAKDDRIRYDNEMKSWE
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