TFAM Antibody - middle region : Biotin (ARP36992_P050-Biotin)

Product Specifications

Gene Name

Transcription factor A, mitochondrial

Gene Aliases

Hmgt, mtTF, tsHM, Hmgts, mtTFA, tsHMG, AI661103

Gene ID

21780

Swiss Prot

P40630

Accession Number

NP_033386

Host

Rabbit

Reactivity

Mouse, Rat, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of mouse TFAM

Target

TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.

Partner Proteins

C1QBP; SNCA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Mouse: 100%; Rabbit: 77%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.