MESP2 Antibody - C-terminal region : Biotin (ARP36921_T100-Biotin)
Selected Variant
ARP36921_T100-Biotin
Size: 100 µL
Product Specifications
Gene Name
Mesoderm posterior 2
Gene Aliases
BHLHc, bHLHc6
Gene ID
17293
Swiss Prot
O08574
Accession Number
NP_032615
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2
Target
Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng) . It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Partner Proteins
Lfng
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Mouse: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
41kDa
References & Citations
Morimoto, M., et al., (2005) Nature 435 (7040), 354-359
Shipping Conditions
Wet Ice
Protein Length
370
NCBI Gene Symbol
MESP2
NCBI GB Accession Number
MESP2
Host or Source
Rabbit
Protein Name
Mesoderm posterior protein 2
Nucleotide Accession Number
NM_008589
Peptide Sequence
SCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGL
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