MESP2 Antibody - C-terminal region : FITC (ARP36921_T100-FITC)
Selected Variant
ARP36921_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
Mesoderm posterior 2
Gene Aliases
BHLHc, bHLHc6
Gene ID
17293
Swiss Prot
O08574
Accession Number
NP_032615
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2
Target
Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng) . It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Partner Proteins
Lfng
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Mouse: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
41kDa
References & Citations
Morimoto, M., et al., (2005) Nature 435 (7040), 354-359
Shipping Conditions
Wet Ice
Protein Length
370
NCBI Gene Symbol
MESP2
NCBI GB Accession Number
MESP2
Host or Source
Rabbit
Protein Name
Mesoderm posterior protein 2
Nucleotide Accession Number
NM_008589
Peptide Sequence
SCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGL
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