FOXH1 Antibody - middle region : Biotin (ARP36853_P050-Biotin)

Product Specifications

Gene Name

Forkhead box H1

Gene Aliases

Fas, Fast1, Fast2, fast-1, fast-2

Gene ID

14106

Swiss Prot

O88621

Accession Number

NP_032015

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of mouse FOXH1

Target

Foxh1 is a transcriptional activator. Foxh1 can recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3' and is required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Foxh1 forms a transcriptionally active complex containing FAST-1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element) .

Partner Proteins

Nkx2-5; Gsc; Smad2; Gtf2a1; Rxrg; Smad3; Alx4; Mef2c

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Mouse: 100%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.