CIITA Antibody - C-terminal region : Biotin (ARP36830_P050-Biotin)
Selected Variant
ARP36830_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Class II transactivator
Gene Aliases
C2t, C2ta, Gm9475, Mhc2ta, EG669998
Gene ID
12265
Swiss Prot
Q3U2P0
Accession Number
NP_031601
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of mouse C2TA
Target
This gene encodes a member of the NOD-like receptor protein family. This protein acts as a transcriptional coactivator and component of the enhanceosome complex to stimulate transcription of MHC class II genes in the adaptive immune response. This protein may also regulate the transcription of MHC class I genes. Mutations in the human gene have been linked to a rare immunodeficiency, bare lymphocyte syndrome, and homozygous knockout mice exhibit many features of this disease. Alternative splicing results in multiple transcript variants encoding different isoforms.
Partner Proteins
Rfxank; Ssbp4; Ssbp3; Gmeb1; Cited4; Tcf3; Nfe2; Hoxa2; Ewsr1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 100%; Human: 79%; Mouse: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
119kDa
References & Citations
Pennini, M.E., et al., (2006) J. Immunol. 176 (7), 4323-4330
Shipping Conditions
Wet Ice
Protein Length
1078
NCBI Gene Symbol
CIITA
NCBI GB Accession Number
CIITA
Host or Source
Rabbit
Protein Name
MHC class II transactivator
Nucleotide Accession Number
NM_007575
Peptide Sequence
MALWESLQQQGEAQLLQAAEEKFTIEPFKAKSPKDVEDLDRLVQTQRLRN
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