CACNB2 Antibody - N-terminal region : Biotin (ARP36765_P050-Biotin)
Product Specifications
Gene Name
Calcium channel, voltage-dependent, beta 2 subunit
Gene Aliases
CAB2, MYSB, CAVB2, CACNLB2
Gene ID
783
Swiss Prot
Q08289
Accession Number
NP_963890
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the n terminal region of human CACNB2
Target
CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4) .
Partner Proteins
REM1; PRKACA
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
73kDa
References & Citations
Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693
Shipping Conditions
Wet Ice
Product Datasheet
Anti-CACNB2 (ARP36765_P050-Biotin) antibody
Protein Length
660
NCBI Gene Symbol
CACNB2
NCBI GB Accession Number
CACNB2
Host or Source
Rabbit
Protein Name
Voltage-dependent L-type calcium channel subunit beta-2
Nucleotide Accession Number
NM_201596
Peptide Sequence
IQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTSSDTTSNSFVR
Subunit
Beta-2
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