ADAR Antibody - C-terminal region : FITC (ARP36712_P050-FITC)

Product Specifications

Gene Name

Adenosine deaminase, RNA-specific

Gene Aliases

DSH, AGS6, G1P1, IFI4, P136, ADAR1, DRADA, DSRAD, IFI-4, K88DSRBP

Gene ID

103

Swiss Prot

P55265

Accession Number

NP_001102

Host

Rabbit

Reactivity

Human, Mouse, Rat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ADAR

Target

ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

UBC; SUMO2; SUMO3; STAU1; STAU2; SUMO1; RPA3; RPA2; RPA1; ERG; SUZ12; EED; EZH2; BMI1; RNF2; rev; FBXO6; TARDBP; UBE2I; HDAC9; XPO1; WHSC1; TGM2; SNRPN; SNRPB; UPF1; DHX9; DDX17; HNRNPM; CAND1; CUL3; HNRNPA1; ELAVL1; HDAC5; tat; ADAR; HDLBP

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Guinea Pig: 92%; Horse: 92%; Human: 92%; Mouse: 91%; Rabbit: 92%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.