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Kl Antibody - N-terminal region : Biotin (ARP36671_P050-Biotin)

Selected Variant

ARP36671_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Klotho

Gene Aliases

Alp, alpha-kl

Gene ID

16591

Swiss Prot

O35082

Accession Number

NP_038851

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig, Rabbit

Target

Kl may have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. It may be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.

Partner Proteins

Trpv5; Fgfr4; Fgfr3; Fgfr2; Fgfr1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 91%; Rabbit: 92%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

116kDa

Shipping Conditions

Wet Ice

Protein Length

1014

NCBI Gene Symbol

KL

NCBI GB Accession Number

Kl

Host or Source

Rabbit

Protein Name

Klotho

Nucleotide Accession Number

NM_013823

Peptide Sequence

GAAPSDSPIVVAPSGAPSPPLSSTGDVASDSYNNVYRDTEGLRELGVTHY

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