MCM5 Antibody - N-terminal region : HRP (ARP36654_T100-HRP)
Selected Variant
ARP36654_T100-HRP
Size: 100 µL
Product Specifications
Gene Name
Minichromosome maintenance complex component 5
Gene Aliases
CDC46, MGORS8, P1-CDC46
Gene ID
4174
Swiss Prot
P33992
Accession Number
NP_006730
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MCM5
Target
The protein encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Partner Proteins
KRTAP10-7; RBPMS; SUMO2; SUMO3; MCMBP; UBC; RNF2; NEK9; MCM3; HSP90AB1; HSP90AA1; FKBP5; MAGED2; CAP1; BAG3; CD81; IGSF8; TCEA1; PNKP; VCAM1; ORC5; ORC1; MCM7; MCM2; ITGA4; FN1; CDKN2A; CDC5L; NOTCH1; MYBBP1A; U2AF1; MCM6; MCM4; HNRNPU; APP; FBXO6; NEDD8
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 79%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
82kDa
References & Citations
Ohtani, K., et al., (1999) Oncogene 18 (14), 2299-2309
Shipping Conditions
Wet Ice
Protein Length
734
NCBI Gene Symbol
MCM5
NCBI GB Accession Number
MCM5
Host or Source
Rabbit
Protein Name
DNA replication licensing factor MCM5
Nucleotide Accession Number
NM_006739
Peptide Sequence
MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTG
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