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TJP1 Antibody - middle region : Biotin (ARP36636_P050-Biotin)

Product Specifications

Gene Name

Tight junction protein 1 (zona occludens 1)

Gene Aliases

ZO-1

Gene ID

7082

Swiss Prot

Q07157

Accession Number

NP_783297

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TJP1

Target

TJP1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. TJP1 may be involved in signal transduction at cell-cell junctions.This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

VMP1; RAPGEF2; LATS2; TJP2; PAN2; DTNA; UBC; SCO2; VAPA; VAPB; ZPR1; NOTCH2; NDUFV2; NDUFS6; SUGP1; RTN4; STRN; PARD3; PARD6A; PRKCI; SIRT7; KHDRBS1; ELAVL1; SSTR3; Cdk1; TUBA1C; TUBB4A; VIM; SPTAN1; PLEC; KRT10; KRT8; KRT1; GJA1; FLNA; ANXA6; ACTN1; ACTN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 92%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 87%; Pig: 93%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

187kDa

References & Citations

Shen, L., (2008) J. Cell Biol. 181 (4), 683-695

Shipping Conditions

Wet Ice

Protein Length

1668

NCBI Gene Symbol

TJP1

NCBI GB Accession Number

TJP1

Host or Source

Rabbit

Protein Name

Tight junction protein ZO-1

Nucleotide Accession Number

NM_175610

Peptide Sequence

QNHVLKQPAVSHPGHRPDKEPNLTYEPQLPYVEKQASRDLEQPTYRYESS

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