TJP1 Antibody - middle region : HRP (ARP36636_P050-HRP)
Product Specifications
Gene Name
Tight junction protein 1 (zona occludens 1)
Gene Aliases
ZO-1
Gene ID
7082
Swiss Prot
Q07157
Accession Number
NP_783297
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TJP1
Target
TJP1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. TJP1 may be involved in signal transduction at cell-cell junctions.This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
Partner Proteins
VMP1; RAPGEF2; LATS2; TJP2; PAN2; DTNA; UBC; SCO2; VAPA; VAPB; ZPR1; NOTCH2; NDUFV2; NDUFS6; SUGP1; RTN4; STRN; PARD3; PARD6A; PRKCI; SIRT7; KHDRBS1; ELAVL1; SSTR3; Cdk1; TUBA1C; TUBB4A; VIM; SPTAN1; PLEC; KRT10; KRT8; KRT1; GJA1; FLNA; ANXA6; ACTN1; ACTN
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 92%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 87%; Pig: 93%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
187kDa
References & Citations
Shen, L., (2008) J. Cell Biol. 181 (4), 683-695
Shipping Conditions
Wet Ice
Protein Length
1668
NCBI Gene Symbol
TJP1
NCBI GB Accession Number
TJP1
Host or Source
Rabbit
Protein Name
Tight junction protein ZO-1
Nucleotide Accession Number
NM_175610
Peptide Sequence
QNHVLKQPAVSHPGHRPDKEPNLTYEPQLPYVEKQASRDLEQPTYRYESS
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