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GJB4 Antibody - middle region : HRP (ARP36633_T100-HRP)

Product Specifications

Gene Name

Gap junction protein, beta 4, 30.3kDa

Gene Aliases

EKV, EKVP2, CX30.3

Gene ID

127534

Swiss Prot

Q9NTQ9

Accession Number

NP_694944

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GJB4

Target

Connexins are homologous four-transmembrane-domain proteins and major components of gap junctions. The GJB4 gene encodes connexin 30.3 (Cx30.3) A mutation in connexin 30.3 is causally involved in erythrokeratodermia variabilis (EKV), a mostly autosomal dominant disorder of keratinization.

Partner Proteins

UBC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Horse: 100%; Human: 100%; Mouse: 86%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

29kDa

References & Citations

Plantard, L., et al., (2003) Hum. Mol. Genet. 12 (24), 3287-3294

Shipping Conditions

Wet Ice

Product Datasheet

Anti-GJB4 (ARP36633_T100-HRP) antibody

Protein Length

266

NCBI Gene Symbol

GJB4

NCBI GB Accession Number

GJB4

Host or Source

Rabbit

Protein Name

Gap junction beta-4 protein

Nucleotide Accession Number

NM_153212

Peptide Sequence

CPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLSKKRGGLWWTYLLSL

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