GJB4 Antibody - middle region : FITC (ARP36633_T100-FITC)
Product Specifications
Gene Name
Gap junction protein, beta 4, 30.3kDa
Gene Aliases
EKV, EKVP2, CX30.3
Gene ID
127534
Swiss Prot
Q9NTQ9
Accession Number
NP_694944
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GJB4
Target
Connexins are homologous four-transmembrane-domain proteins and major components of gap junctions. The GJB4 gene encodes connexin 30.3 (Cx30.3) A mutation in connexin 30.3 is causally involved in erythrokeratodermia variabilis (EKV), a mostly autosomal dominant disorder of keratinization.
Partner Proteins
UBC
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 92%; Horse: 100%; Human: 100%; Mouse: 86%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
29kDa
References & Citations
Plantard, L., et al., (2003) Hum. Mol. Genet. 12 (24), 3287-3294
Shipping Conditions
Wet Ice
Protein Length
266
NCBI Gene Symbol
GJB4
NCBI GB Accession Number
GJB4
Host or Source
Rabbit
Protein Name
Gap junction beta-4 protein
Nucleotide Accession Number
NM_153212
Peptide Sequence
CPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLSKKRGGLWWTYLLSL
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