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GJC2 Antibody - middle region : Biotin (ARP36621_P050-Biotin)

Product Specifications

Gene Name

Gap junction protein, gamma 2, 47kDa

Gene Aliases

Cx47, HLD2, GJA12, SPG44, CX46.6, LMPH1C, LMPHM3, PMLDAR

Gene ID

57165

Swiss Prot

Q5T442

Accession Number

NP_065168

Host

Rabbit

Reactivity

Human, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GJC2

Target

GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

Partner Proteins

ALB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

GJC2 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Human: 100%; Rabbit: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

References & Citations

Henneke, M., (2008) Neurology 70 (10), 748-754

Shipping Conditions

Wet Ice

Protein Length

439

NCBI Gene Symbol

GJC2

NCBI GB Accession Number

GJC2

Host or Source

Rabbit

Protein Name

Gap junction gamma-2 protein

Nucleotide Accession Number

NM_020435

Peptide Sequence

APASRTGSATSAGTVGEQGRPGTHERPGAKPRAGSEKGSASSRDGKTTVW

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