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GJC2 Antibody - middle region : HRP (ARP36621_P050-HRP)

Product Specifications

Gene Name

Gap junction protein, gamma 2, 47kDa

Gene Aliases

Cx47, HLD2, GJA12, SPG44, CX46.6, LMPH1C, LMPHM3, PMLDAR

Gene ID

57165

Swiss Prot

Q5T442

Accession Number

NP_065168

Host

Rabbit

Reactivity

Human, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GJC2

Target

GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

Partner Proteins

ALB

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

GJC2 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Human: 100%; Rabbit: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

References & Citations

Henneke, M., (2008) Neurology 70 (10), 748-754

Shipping Conditions

Wet Ice

Protein Length

439

NCBI Gene Symbol

GJC2

NCBI GB Accession Number

GJC2

Host or Source

Rabbit

Protein Name

Gap junction gamma-2 protein

Nucleotide Accession Number

NM_020435

Peptide Sequence

APASRTGSATSAGTVGEQGRPGTHERPGAKPRAGSEKGSASSRDGKTTVW

Frequently Asked Questions

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