GJC2 Antibody - middle region : FITC (ARP36621_P050-FITC)
Product Specifications
Gene Name
Gap junction protein, gamma 2, 47kDa
Gene Aliases
Cx47, HLD2, GJA12, SPG44, CX46.6, LMPH1C, LMPHM3, PMLDAR
Gene ID
57165
Swiss Prot
Q5T442
Accession Number
NP_065168
Host
Rabbit
Reactivity
Human, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GJC2
Target
GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
Partner Proteins
ALB
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Sample Type
GJC2 is supported by BioGPS gene expression data to be expressed in HEK293T
Concentration
0.5 mg/ml
Homology
Human: 100%; Rabbit: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47kDa
References & Citations
Henneke, M., (2008) Neurology 70 (10), 748-754
Shipping Conditions
Wet Ice
Protein Length
439
NCBI Gene Symbol
GJC2
NCBI GB Accession Number
GJC2
Host or Source
Rabbit
Protein Name
Gap junction gamma-2 protein
Nucleotide Accession Number
NM_020435
Peptide Sequence
APASRTGSATSAGTVGEQGRPGTHERPGAKPRAGSEKGSASSRDGKTTVW
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