GJA8 Antibody - middle region : Biotin (ARP36612_P050-Biotin)
Product Specifications
Gene Name
Gap junction protein, alpha 8, 50kDa
Gene Aliases
CAE, CAE1, CX50, CZP1, MP70, CTRCT1
Gene ID
2703
Swiss Prot
P48165
Accession Number
NP_005258
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GJA8
Target
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1) .
Partner Proteins
TJP1; MIP
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 79%; Horse: 79%; Human: 100%; Mouse: 79%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
References & Citations
Arora, A., (2008) J. Med. Genet. 45 (3), 155-160
Shipping Conditions
Wet Ice
Protein Length
433
NCBI Gene Symbol
GJA8
NCBI GB Accession Number
GJA8
Host or Source
Rabbit
Protein Name
Gap junction alpha-8 protein
Nucleotide Accession Number
NM_005267
Peptide Sequence
EEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPEL
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