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GJA8 Antibody - middle region : Biotin (ARP36612_P050-Biotin)

Product Specifications

Gene Name

Gap junction protein, alpha 8, 50kDa

Gene Aliases

CAE, CAE1, CX50, CZP1, MP70, CTRCT1

Gene ID

2703

Swiss Prot

P48165

Accession Number

NP_005258

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GJA8

Target

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1) .

Partner Proteins

TJP1; MIP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 79%; Horse: 79%; Human: 100%; Mouse: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

References & Citations

Arora, A., (2008) J. Med. Genet. 45 (3), 155-160

Shipping Conditions

Wet Ice

Protein Length

433

NCBI Gene Symbol

GJA8

NCBI GB Accession Number

GJA8

Host or Source

Rabbit

Protein Name

Gap junction alpha-8 protein

Nucleotide Accession Number

NM_005267

Peptide Sequence

EEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPEL

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