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GJB1 Antibody - C-terminal region : HRP (ARP36600_T100-HRP)

Selected Variant

ARP36600_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Gap junction protein, beta 1, 32kDa

Gene Aliases

CMTX, CX32, CMTX1

Gene ID

2705

Swiss Prot

P08034

Accession Number

NP_000157

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GJB1

Target

This gene encodes for a Connexin 32 protein. A large Charcot-Marie-Tooth disease family has been identified with a novel mutation in the Cx32 P2 promoter region at position -526bp. Cx32 mutants that are associated with a CNS phenotype may have toxic effects in oligodendrocytes.

Partner Proteins

UBC; VKORC1; APP; CNST; OCLN; PRKACA; SRC; PRKCA; GJB2; CALM1; CAV1; JUP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

References & Citations

Dagli, M.L., et al., (2004) Carcinogenesis 25 (4), 483-492

Shipping Conditions

Wet Ice

Protein Length

283

NCBI Gene Symbol

GJB1

NCBI GB Accession Number

GJB1

Host or Source

Rabbit

Protein Name

Gap junction beta-1 protein

Nucleotide Accession Number

NM_000166

Peptide Sequence

GFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC

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