Anxa6 Antibody - C-terminal region : Biotin (ARP36582_T100-Biotin)
Product Specifications
Gene Name
Annexin A6
Gene Aliases
P68, p70, ANX6, CBP68, CPB-II
Gene ID
309
Swiss Prot
P08133
Accession Number
NP_001146
Host
Rabbit
Reactivity
Human, Mouse, Rat, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human Anxa6
Target
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Partner Proteins
UBC; MDM2; THOP1; PLS3; MTAP; IDH1; HPRT1; GOT1; ADSS; POLE3; NAMPT; UBE2H; ATP4A; METTL18; MLH1; SNCA; CUL5; SIRT7; PRKCA; TJP1; CD4; H2AFX; CDC73; TPD52; S100B; S100A1; RASA1; CR2; A2M; tax
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Sample Type
Anxa6 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Guinea Pig: 79%; Human: 100%; Mouse: 86%; Rabbit: 79%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
74kDa
References & Citations
Cuschieri, J., et al., (2005) Surgery 138 (2), 158-164
Shipping Conditions
Wet Ice
Protein Length
673
NCBI Gene Symbol
ANXA6
NCBI GB Accession Number
Anxa6
Host or Source
Rabbit
Protein Name
Annexin A6
Nucleotide Accession Number
NM_001155
Peptide Sequence
SDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDK
More Discoveries
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