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Anxa6 Antibody - C-terminal region : Biotin (ARP36582_T100-Biotin)

Product Specifications

Gene Name

Annexin A6

Gene Aliases

P68, p70, ANX6, CBP68, CPB-II

Gene ID

309

Swiss Prot

P08133

Accession Number

NP_001146

Host

Rabbit

Reactivity

Human, Mouse, Rat, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human Anxa6

Target

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.

Partner Proteins

UBC; MDM2; THOP1; PLS3; MTAP; IDH1; HPRT1; GOT1; ADSS; POLE3; NAMPT; UBE2H; ATP4A; METTL18; MLH1; SNCA; CUL5; SIRT7; PRKCA; TJP1; CD4; H2AFX; CDC73; TPD52; S100B; S100A1; RASA1; CR2; A2M; tax

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

Anxa6 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Guinea Pig: 79%; Human: 100%; Mouse: 86%; Rabbit: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

References & Citations

Cuschieri, J., et al., (2005) Surgery 138 (2), 158-164

Shipping Conditions

Wet Ice

Protein Length

673

NCBI Gene Symbol

ANXA6

NCBI GB Accession Number

Anxa6

Host or Source

Rabbit

Protein Name

Annexin A6

Nucleotide Accession Number

NM_001155

Peptide Sequence

SDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDK

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