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ANXA1 Antibody - N-terminal region : FITC (ARP36568_T100-FITC)

Selected Variant

ARP36568_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Annexin A1

Gene Aliases

ANX1, LPC1

Gene ID

301

Swiss Prot

P04083

Accession Number

NP_000691

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA1

Target

ANXA1 encodes a protein that belongs to a family of Ca (2+) -dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Partner Proteins

UBC; MEIS2; SUMO2; SUMO3; WWOX; ZBTB1; HECW2; YWHAQ; ATP4A; UBD; BAG3; HMGA1; VCAM1; ITGA4; FN1; ATF2; ANXA4; RIPK1; IKBKG; RELA; CUL5; CDK2; SIRT7; ANXA5; ANXA1; KLHL23; LRIF1; OTUB1; C1orf123; CSAD; C14orf1; FAF1; COPS6; CCT7; KMT2B; UNC119; SUMO1; UBE2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Guinea Pig: 79%; Human: 100%; Mouse: 83%; Rat: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

References & Citations

Ernst, S., et al., (2004) J. Immunol. 172 (12), 7669-7676

Shipping Conditions

Wet Ice

Protein Length

346

NCBI Gene Symbol

ANXA1

NCBI GB Accession Number

ANXA1

Host or Source

Rabbit

Protein Name

Annexin RuleBase RU003540

Nucleotide Accession Number

NM_000700

Peptide Sequence

WFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVD

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