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ARNT Antibody - middle region : Biotin (ARP36562_P050-Biotin)

Selected Variant

ARP36562_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Aryl hydrocarbon receptor nuclear translocator

Gene Aliases

HIF1B, TANGO, bHLHe2, HIF1BETA, HIF-1beta, HIF1-beta, HIF-1-beta

Gene ID

405

Swiss Prot

P27540

Accession Number

NP_001184254.1

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ARNT

Target

This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 93%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Sheep: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

Shipping Conditions

Wet Ice

Protein Length

416

NCBI Gene Symbol

ARNT

NCBI GB Accession Number

ARNT

Host or Source

Rabbit

Protein Name

Aryl hydrocarbon receptor nuclear translocator

Nucleotide Accession Number

NM_001197325.1

Peptide Sequence

QSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLT

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