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WRNIP1 Antibody - N-terminal region : Biotin (ARP36470_P050-Biotin)

Selected Variant

ARP36470_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Werner helicase interacting protein 1

Gene Aliases

WHIP, FAP93, CFAP93, bA420G6.2

Gene ID

56897

Swiss Prot

Q96S55

Accession Number

NP_569079

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human WRNIP1

Target

Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.

Partner Proteins

UBC; RNF31; PIN1; ELP2; ELP3; TRIM28; HDAC11; EPAS1; VCP; SRSF4; SMAD2; RAD18; NUP107; WRNIP1; FGFR1OP; POLD1; ABL1; SUMO2; TOLLIP; DDX58; USP11; OSBPL10; USP25; POLD4; POLD2; WRN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 79%; Rat: 100%; Yeast: 77%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

72kDa

References & Citations

Tsurimoto, T., et al., (2005) Genes Cells 10 (1), 13-22

Shipping Conditions

Wet Ice

Protein Length

640

NCBI Gene Symbol

WRNIP1

NCBI GB Accession Number

WRNIP1

Host or Source

Rabbit

Protein Name

ATPase WRNIP1

Nucleotide Accession Number

NM_130395

Peptide Sequence

PGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPT

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