DDX28 Antibody - N-terminal region : Biotin (ARP36457_P050-Biotin)
Product Specifications
Gene Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
Gene Aliases
MDDX28
Gene ID
55794
Swiss Prot
Q9NUL7
Accession Number
NP_060850
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DDX28
Target
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX28 is an RNA-dependent ATPase. DDX28 is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus.
Partner Proteins
MRPL52; TMEM43; MRPL57; MRPL9; MRPL11; MRPL32; MRPL17; MFF; ATP6V1H; ATP6V1D; MRPL2; MRPL42; TCIRG1; RAB11B; LAMTOR3; RBMS2; PCDH7; ILF2; ICT1; ATP6V1A; CUL3; SH3KBP1; HNRNPA1; Ybx1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Human: 100%; Mouse: 83%; Pig: 85%; Rat: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
59kDa
References & Citations
Valgardsdottir, R. (2003) J. Biol. Chem. 278 (23), 21146-21154
Shipping Conditions
Wet Ice
Protein Length
540
NCBI Gene Symbol
DDX28
NCBI GB Accession Number
DDX28
Host or Source
Rabbit
Protein Name
Probable ATP-dependent RNA helicase DDX28
Nucleotide Accession Number
NM_018380
Peptide Sequence
FSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQS
Frequently Asked Questions
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