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DDX28 Antibody - N-terminal region : FITC (ARP36457_P050-FITC)

Product Specifications

Gene Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 28

Gene Aliases

MDDX28

Gene ID

55794

Swiss Prot

Q9NUL7

Accession Number

NP_060850

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DDX28

Target

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX28 is an RNA-dependent ATPase. DDX28 is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus.

Partner Proteins

MRPL52; TMEM43; MRPL57; MRPL9; MRPL11; MRPL32; MRPL17; MFF; ATP6V1H; ATP6V1D; MRPL2; MRPL42; TCIRG1; RAB11B; LAMTOR3; RBMS2; PCDH7; ILF2; ICT1; ATP6V1A; CUL3; SH3KBP1; HNRNPA1; Ybx1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Human: 100%; Mouse: 83%; Pig: 85%; Rat: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Valgardsdottir, R. (2003) J. Biol. Chem. 278 (23), 21146-21154

Shipping Conditions

Wet Ice

Protein Length

540

NCBI Gene Symbol

DDX28

NCBI GB Accession Number

DDX28

Host or Source

Rabbit

Protein Name

Probable ATP-dependent RNA helicase DDX28

Nucleotide Accession Number

NM_018380

Peptide Sequence

FSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQS

Frequently Asked Questions

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