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HELLS Antibody - middle region : HRP (ARP36449_P050-HRP)

Product Specifications

Gene Name

Helicase, lymphoid-specific

Gene Aliases

LSH, ICF4, PASG, SMARCA6, Nbla10143

Gene ID

3070

Swiss Prot

Q9NRZ9

Accession Number

NP_060533

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HELLS

Target

HELLS is a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis.This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Partner Proteins

UBC; VCP; APP; SUMO2; E2F3; SMARCAD1; MYC; HDAC2; HDAC1; DNMT3B; DNMT1; RPAP2; RPAP3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

HELLS is supported by BioGPS gene expression data to be expressed in HepG2, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

References & Citations

Myant, K. (2008) Mol. Cell. Biol. 28 (1), 215-226

Shipping Conditions

Wet Ice

Protein Length

838

NCBI Gene Symbol

HELLS

NCBI GB Accession Number

HELLS

Host or Source

Rabbit

Protein Name

Lymphoid-specific helicase

Nucleotide Accession Number

NM_018063

Peptide Sequence

QSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSD

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