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DHX30 Antibody - N-terminal region : Biotin (ARP36425_P050-Biotin)

Product Specifications

Gene Name

DEAH (Asp-Glu-Ala-His) box polypeptide 30

Gene Aliases

DDX30, RETCOR, NEDMIAL

Gene ID

22907

Swiss Prot

Q7L2E3

Accession Number

NP_055781

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DHX30

Target

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DHX30 is a member of this family. The protein has 97% sequence identity with the mouse HELG protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein has 97% sequence identity with the mouse HELG protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Partner Proteins

SUMO2; SUMO3; IVNS1ABP; STAU1; GRSF1; UBC; SUMO1; NEDD8; Fbxl16; WWOX; SUZ12; RNF2; EZH2; NEDD4; TARDBP; HNRNPD; EIF2AK2; SKIL; FN1; ESR1; NDUFA2; ILF3; GNAI2; RAB31; GRK5; CAND1; COPS5; CUL1; CUL3; CUL4B; CUL5; SIRT7; HNRNPA1; HDGF; DHX58; OAS3; Sgol2; Y

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

129kDa

References & Citations

Zhou, Y., (2008) Virology 372 (1), 97-106

Shipping Conditions

Wet Ice

Protein Length

1155

NCBI Gene Symbol

DHX30

NCBI GB Accession Number

DHX30

Host or Source

Rabbit

Protein Name

Putative ATP-dependent RNA helicase DHX30

Nucleotide Accession Number

NM_014966

Peptide Sequence

AASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLH

Frequently Asked Questions

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