DDX48 Antibody - middle region : Biotin (ARP36422_T100-Biotin)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 4A3

Gene Aliases

Fal1, RCPS, DDX48, MUK34, NUK34, NMP265, eIF4AIII, eIF4A-III, eIF-4A-III

Gene ID

9775

Swiss Prot

P38919

Accession Number

NP_055555

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DDX48

Target

DDX48 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Partner Proteins

CDCA7L; PDCD4; HUWE1; POLDIP3; HAUS1; SUMO2; SUMO3; STAU1; UBC; LIN28B; SUMO1; WWOX; EED; RNF2; BMI1; SUZ12; ANP32A; PKM; NPLOC4; IPO11; PDLIM5; PLIN3; SRP14; RAD23B; AARS; FBXO6; SRPK2; SRPK1; UPF1; SMG1; RBM8A; ITGA4; CWC22; EEF2K; VCAM1; FN1; TRA2B; HN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Sample Type

EIF4A3 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.