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EIF4A3 Antibody - N-terminal region : FITC (ARP36421_P050-FITC)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 4A3

Gene Aliases

Fal1, RCPS, DDX48, MUK34, NUK34, NMP265, eIF4AIII, eIF4A-III, eIF-4A-III

Gene ID

9775

Swiss Prot

P38919

Accession Number

NP_055555

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4A3

Target

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Partner Proteins

CDCA7L; PDCD4; HUWE1; POLDIP3; HAUS1; SUMO2; SUMO3; STAU1; UBC; LIN28B; SUMO1; WWOX; EED; RNF2; BMI1; SUZ12; ANP32A; PKM; NPLOC4; IPO11; PDLIM5; PLIN3; SRP14; RAD23B; AARS; FBXO6; SRPK2; SRPK1; UPF1; SMG1; RBM8A; ITGA4; CWC22; EEF2K; VCAM1; FN1; TRA2B; HN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

EIF4A3 is supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 85%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-EIF4A3 (ARP36421_P050-FITC) antibody

Protein Length

411

NCBI Gene Symbol

EIF4A3

NCBI GB Accession Number

EIF4A3

Host or Source

Rabbit

Protein Name

Eukaryotic initiation factor 4A-III

Nucleotide Accession Number

NM_014740

Peptide Sequence

RGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCL

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