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DDX58 Antibody - middle region : HRP (ARP36416_P050-HRP)

Selected Variant

ARP36416_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

Gene Aliases

RIG1, RIGI, RIG-I, RLR-1, SGMRT2

Gene ID

23586

Swiss Prot

O95786

Accession Number

NP_055129

Host

Rabbit

Reactivity

Human, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DDX58

Target

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein

Partner Proteins

MAVS; TRIM25; RNF135; TRIM26; UBC; MEX3C; USP21; USP3; TBK1; IKBKE; IKBKG; Casp12; NLRC5; DDX58; USP4; MBP; IRF3; SRC; TSPAN6; TRIM32; ISG15; PRKCG; PRKCB; PRKCA; WRNIP1; RNF31; RAI14; RBCK1; PRKRIR; UBE2D3; UBE2D2; UBE2D1; UBE2K; CYLD

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Horse: 79%; Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

106kDa

References & Citations

Miyazaki, M., (2008) J. Med. Virol. 80 (6), 980-988

Shipping Conditions

Wet Ice

Protein Length

925

NCBI Gene Symbol

DDX58

NCBI GB Accession Number

DDX58

Host or Source

Rabbit

Protein Name

Probable ATP-dependent RNA helicase DDX58

Nucleotide Accession Number

NM_014314

Peptide Sequence

EECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIH

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