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RAD54B Antibody - middle region : Biotin (ARP36408_P050-Biotin)

Product Specifications

Gene Name

RAD54 homolog B (S. cerevisiae)

Gene Aliases

RDH54

Gene ID

25788

Swiss Prot

Q9Y620

Accession Number

NP_036547

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RAD54B

Target

RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.

Partner Proteins

TCEANC; ATPAF2; ANKRD36BP1; ENKD1; MYO15B; GMCL1; RAD54B; CDC23; SUMO1; PRKAA1; FUS; HECW2; PSMA1; RAD51; NUDT18; NIF3L1; TCEB3; COPS6; SUMO2; UBC; WRN; ZNF580; LNX1; TRAPPC6A; RIBC2; CCDC33; UBE2I; GORASP2; DYRK2; DMC1; CSNK1E; CD2BP2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

RAD54B is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

103kDa

References & Citations

Brys, M., (2007) Pol J Pathol 58 (1), 3-6

Shipping Conditions

Wet Ice

Protein Length

910

NCBI Gene Symbol

RAD54B

NCBI GB Accession Number

RAD54B

Host or Source

Rabbit

Protein Name

DNA repair and recombination protein RAD54B

Nucleotide Accession Number

NM_012415

Peptide Sequence

NSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT

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