DDX42 Antibody - N-terminal region : Biotin (ARP36403_P050-Biotin)
Product Specifications
Gene Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Gene Aliases
RHELP, RNAHP, SF3B8, DDX42P, SF3b125
Gene ID
11325
Swiss Prot
Q86XP3
Accession Number
NP_031398
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DDX42
Target
DDX42 is a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX42 is a ATP-dependent RNA helicase. DDX42 binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. It also mediates RNA duplex formation thereby displacing the single-strand RNA binding protein.This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.
Partner Proteins
FUS; UBC; SUMO1; EED; SHFM1; FBXO25; LMNA; PRPF19; U2SURP; SF3A1; SF3B4; SNRPC; ITGA4; DHX15; PIN4; KAL1; EPRS; APP; PHF20; NOSIP; RPL36; FOXJ3; TCERG1; SYNCRIP; RPS6KA4; SUMO3; ISG15; SIRT7; SF3A2; MEPCE; RUVBL2; RUVBL1; RECQL5; SF3B1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
103kDa
References & Citations
Will, C.L., et al., (2002) EMBO J. 21 (18), 4978-4988
Shipping Conditions
Wet Ice
Protein Length
938
NCBI Gene Symbol
DDX42
NCBI GB Accession Number
DDX42
Host or Source
Rabbit
Protein Name
ATP-dependent RNA helicase DDX42
Nucleotide Accession Number
NM_007372
Peptide Sequence
PLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYM
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog