DDX23 Antibody - C-terminal region: Biotin (ARP36376_T100-Biotin)
Product Specifications
Gene Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Gene Aliases
Prp28, PRPF28, U5-100K, SNRNP100, U5-100KD
Gene ID
9416
Swiss Prot
Q9BUQ8
Accession Number
NP_004809
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human DDX23
Target
DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.
Partner Proteins
SUMO2; STAU1; UBC; RPA3; RPA2; RPA1; ERG; SUZ12; WBP4; PRPF4B; PAXIP1; PHF5A; SF3A3; SART1; THOC5; PURA; RNU6ATAC; RNU4ATAC; TERF2IP; TERF1; SIRT7; HNRNPA1; SF3A2; SUMO1; Prpf8; TOP1; SNW1; TP63; TP73; MEPCE; USP39; PRPF4; OTUB1; RNPS1; CD2BP2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Sample Type
DDX23 is strongly supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
90kDa
Shipping Conditions
Wet Ice
Protein Length
820
NCBI Gene Symbol
DDX23
Protein Name
Probable ATP-dependent RNA helicase DDX23
Nucleotide Accession Number
NM_004818
Curated Selection
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