BAT1 Antibody - C-terminal region : Biotin (ARP36372_P050-Biotin)

Product Specifications

Gene Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

Gene Aliases

BAT1, UAP56, D6S81E

Gene ID

7919

Swiss Prot

Q13838

Accession Number

NP_542165

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human BAT1

Target

BAT1 is a member of the DEAD protein family of ATP-dependent RNA helicases. Members of this family are involved in a number of cellular functions including initiation of translation, RNA splicing, and ribosome assembly. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This protein is a negative regulator of inflammation. It is also thought to be a translation initiation factor. This gene is a strong candidate gene for rheumatoid arthritis. There are multiple alternatively spliced transcript variants known for this gene but only two have been fully described. Both of these variants encode the same isoform. This gene has been found to have multiple polyadenylation sites.

Partner Proteins

THOC3; THOC2; ALYREF; NCBP1; STAU1; SHFM1; UBC; MDM2; WWOX; SUZ12; EED; RNF2; BMI1; RBBP4; C12orf10; NDRG1; HSPD1; GSR; SRPK2; UBD; VCAM1; ITGA4; IL7R; FN1; ATF2; BARD1; WIBG; MAGOHB; WDR74; VPS33B; LSM4; THOC1; RBM8A; DHX38; TXNL1; UBE3A; RPS7; EIF4A2; R

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

DDX39B is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.