DDX5 Antibody - C-terminal region: FITC (ARP36365_T100-FITC)

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX5 encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. DDX5 consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.

FUS; ESR1; DROSHA; MAPKAPK2; UBC; TP53; TUBGCP3; AURKB; SPRTN; AURKA; SUMO2; SUMO3; MDM2; CEP250; STAU1; RPA3; RPA2; RPA1; EED; EZH2; RNF2; SUZ12; rev; DDX17; PABPC4; PRPSAP1; PIN1; LRSAM1; FKBP10; ERO1L; DBNL; WDR4; PARK2; FBXO6; MAPK10; SP1; TARDBP; UBD

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.