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AKAP1 Antibody - C-terminal region : HRP (ARP36334_P050-HRP)

Product Specifications

Gene Name

A kinase (PRKA) anchor protein 1

Gene Aliases

AKAP, PRKA1, AKAP84, TDRD17, AKAP121, AKAP149, D-AKAP1, PPP1R43, SAKAP84

Gene ID

8165

Swiss Prot

Q92667

Accession Number

NP_644804

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AKAP1

Target

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP1 is a member of the AKAP family. It binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.

Partner Proteins

MDM2; PRKACB; PRKACA; UBC; APP; TP73; USP7; PPP1CA; MYCBP; PTPN21; CAV1; PRKAR1A; PRKAR2B; PRKAR1B; PRKAR2A; AMY1C; SIAH2; MAATS1; AMY1A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

65kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-AKAP1 (ARP36334_P050-HRP) antibody

Protein Length

593

NCBI Gene Symbol

AKAP1

NCBI GB Accession Number

AKAP1

Host or Source

Rabbit

Protein Name

A-kinase anchor protein 1, mitochondrial

Nucleotide Accession Number

NM_139275

Peptide Sequence

VPFSNGVLKGELSDLGAEDGWTMDAEADHSGVAAPPPGKRGTLITRCPGF

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