AKAP7 Antibody - N-terminal region : HRP (ARP36333_P050-HRP)
Selected Variant
ARP36333_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
A kinase (PRKA) anchor protein 7
Gene Aliases
AKAP15, AKAP18
Gene ID
9465
Swiss Prot
O43687
Accession Number
NP_619539
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human AKAP7
Target
AKAP7 is a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.
Partner Proteins
CEP76; ROPN1; SPA17; PRKAR2B; PRKACB; PRKACA; MEPCE; USP4; PRKAR1A; PRKAR2A
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
11kDa
References & Citations
Brown, R.L., et al., (2003) Biochem. Biophys. Res. Commun. 306 (2), 394-401
Shipping Conditions
Wet Ice
Protein Length
104
NCBI Gene Symbol
AKAP7
NCBI GB Accession Number
AKAP7
Host or Source
Rabbit
Protein Name
A-kinase anchor protein 7 isoforms alpha and beta
Nucleotide Accession Number
NM_138633
Peptide Sequence
MGQLCCFPFSRDEGKISELESSSSAVLQRYSKDIPSWSSGEKNGGEPDDA
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