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ELOA2 Antibody - middle region : Biotin (ARP35916_P050-Biotin)

Product Specifications

Gene Name

Elongin A2

Gene Aliases

HsT832, TCEB3B, TCEB3L

Gene ID

51224

Swiss Prot

Q8IYF1

Accession Number

NP_057511

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TCEB3B

Target

This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.

Partner Proteins

ZCCHC10; HECW2; CDK6; COIL; TCEB2; TCEB1; CEP70; KXD1; KRTAP4-12; ZBTB43; SOHLH2; CALCOCO2; TRIM37; CBX5; DVL2; TRAF2; ZNF165

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TCEB3B is supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

84kDa

References & Citations

Lim, J., (2006) Cell 125 (4), 801-814

Shipping Conditions

Wet Ice

Protein Length

753

NCBI Gene Symbol

ELOA2

NCBI GB Accession Number

ELOA2

Host or Source

Rabbit

Protein Name

Elongin-A2

Nucleotide Accession Number

NM_016427

Peptide Sequence

QAGSGQRVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEE

Subunit

A2

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