ELOA2 Antibody - middle region : HRP (ARP35916_P050-HRP)
Product Specifications
Gene Name
Elongin A2
Gene Aliases
HsT832, TCEB3B, TCEB3L
Gene ID
51224
Swiss Prot
Q8IYF1
Accession Number
NP_057511
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TCEB3B
Target
This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
Partner Proteins
ZCCHC10; HECW2; CDK6; COIL; TCEB2; TCEB1; CEP70; KXD1; KRTAP4-12; ZBTB43; SOHLH2; CALCOCO2; TRIM37; CBX5; DVL2; TRAF2; ZNF165
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
TCEB3B is supported by BioGPS gene expression data to be expressed in OVCAR3
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
84kDa
References & Citations
Lim, J., (2006) Cell 125 (4), 801-814
Shipping Conditions
Wet Ice
Protein Length
753
NCBI Gene Symbol
ELOA2
NCBI GB Accession Number
ELOA2
Host or Source
Rabbit
Protein Name
Elongin-A2
Nucleotide Accession Number
NM_016427
Peptide Sequence
QAGSGQRVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEE
Subunit
A2
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