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VSX1 Antibody - middle region : Biotin (ARP35882_P050-Biotin)

Product Specifications

Gene Name

Visual system homeobox 1

Gene Aliases

PPD, KTCN, PPCD, RINX, KTCN1, PPCD1, CAASDS

Gene ID

30813

Swiss Prot

Q9NZR4

Accession Number

NP_055403

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human VSX1

Target

VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in VSX1 can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

VSX1 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

References & Citations

Tang, Y.G., (2008) Cornea 27 (2), 189-192

Shipping Conditions

Wet Ice

Protein Length

365

NCBI Gene Symbol

VSX1

NCBI GB Accession Number

VSX1

Host or Source

Rabbit

Protein Name

Visual system homeobox 1

Nucleotide Accession Number

NM_014588

Peptide Sequence

LAGLWGSDHFKEGSSQSESGSQRGSDKVSPENGLEDVAIDLSSSARQETK

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