RXRG Antibody - N-terminal region : FITC (ARP35815_T100-FITC)
Product Specifications
Gene Name
Retinoid X receptor, gamma
Gene Aliases
RXRC, NR2B3
Gene ID
6258
Swiss Prot
P48443
Accession Number
NP_008848
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human RXRG
Target
RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA) . This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Partner Proteins
NR1H3; NR1H2; RARB; RARA; MPPED2; UBC; CUL1; DCK; NR1H4; NCOR2; NR1I2; VDR; THRB; RARG; PPARD; MAP4; CAMK2B; CEBPZ; HOXD4; AJUBA; RPAP2; LRSAM1; PNO1; CHGB; THRA; NCOA6; PPARG; SRF; CREBBP; PPARA; NR4A1; Nr0b2; ITGB3BP
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
References & Citations
Klopper, J.P., et al., (2004) Mol. Cancer Ther. 3 (8), 1011-1020
Shipping Conditions
Wet Ice
Product Datasheet
Anti-RXRG (ARP35815_T100-FITC) antibody
Protein Length
463
NCBI Gene Symbol
RXRG
NCBI GB Accession Number
RXRG
Host or Source
Rabbit
Protein Name
Retinoic acid receptor RXR-gamma
Nucleotide Accession Number
NM_006917
Peptide Sequence
GSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLP
Curated Selection
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