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KLF4 Antibody - N-terminal region : FITC (ARP35721_T100-FITC)

Product Specifications

Gene Name

Kruppel-like factor 4 (gut)

Gene Aliases

EZF, GKLF

Gene ID

9314

Swiss Prot

O43474

Accession Number

NP_004226

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KLF4

Target

The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.

Partner Proteins

EP300; CREBBP; SETD7; CTBP1; Dlg4; APP; CUL2; VHL; UBC; TCEB2; SP1; RELA; PRKCD; PPARG; SMARCA4; HDAC2; HDAC7; KAT5; HDAC1; HDAC5; ELK1; KLF6; TP53

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 80%; Dog: 87%; Horse: 87%; Human: 100%; Pig: 80%; Rabbit: 85%; Sheep: 80%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Yoon, H.S., (2005) Oncogene 24 (25), 4017-4025

Shipping Conditions

Wet Ice

Product Datasheet

Anti-KLF4 (ARP35721_T100-FITC) antibody

Protein Length

470

NCBI Gene Symbol

KLF4

NCBI GB Accession Number

KLF4

Host or Source

Rabbit

Protein Name

Krueppel-like factor 4

Nucleotide Accession Number

NM_004235

Peptide Sequence

GAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESVAATVSSSAS

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