SMPD1 Antibody - middle region : Biotin (ARP35631_P050-Biotin)
Selected Variant
ARP35631_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Sphingomyelin phosphodiesterase 1
Gene Aliases
ASM, NPD, ASMASE
Gene ID
6609
Swiss Prot
P17405
Accession Number
NP_000534.3
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SMPD1
Target
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) . Multiple transcript variants encoding different isoforms have been identified.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 83%; Dog: 87%; Guinea Pig: 87%; Horse: 80%; Human: 100%; Mouse: 80%; Rabbit: 87%; Rat: 87%; Sheep: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
18kDa
Shipping Conditions
Wet Ice
Protein Length
171
NCBI Gene Symbol
SMPD1
NCBI GB Accession Number
SMPD1
Host or Source
Rabbit
Protein Name
Sphingomyelin phosphodiesterase
Nucleotide Accession Number
NM_000543.4
Peptide Sequence
RLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIA
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