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SMPD1 Antibody - middle region: FITC (ARP35630_P050-FITC)

Product Specifications

Gene Name

Sphingomyelin phosphodiesterase 1, acid lysosomal

Gene Aliases

ASM, NPD, ASMASE

Gene ID

6609

Swiss Prot

P17405

Accession Number

NP_000534

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SMPD1

Target

SMPD1 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) .

Partner Proteins

ELAVL1; DUSP23; NR1H2; ANXA7; ANXA4; NGFRAP1; ASAH1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 86%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

65kDa

Shipping Conditions

Wet Ice

Protein Length

631

NCBI Gene Symbol

SMPD1

Protein Name

Sphingomyelin phosphodiesterase

Nucleotide Accession Number

NM_000543

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