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CACNB2 Antibody - middle region : Biotin (ARP35602_P050-Biotin)

Product Specifications

Gene Name

Calcium channel, voltage-dependent, beta 2 subunit

Gene Aliases

CAB2, MYSB, CAVB2, CACNLB2

Gene ID

783

Swiss Prot

Q6TME3

Accession Number

NP_963891

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CACNB2

Target

CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4) .

Partner Proteins

REM1; PRKACA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

71

Shipping Conditions

Wet Ice

Protein Length

636

NCBI Gene Symbol

CACNB2

NCBI GB Accession Number

CACNB2

Host or Source

Rabbit

Protein Name

Voltage-gated calcium channel beta 2 subunit splice variant CavB2cN1 EMBL AAQ97608.1

Nucleotide Accession Number

NM_201597

Peptide Sequence

SRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVG

Subunit

Beta-2

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